Methods for cardiac resynchronization therapy in patients with heart failure and intraventricular conduction disturbances

Main Article Content

O. I. Semeniuk
M. S. Sorokivskyy
U. P. Chernyaha-Royko
B. B. Kravchuk
O. J. Zharinov

Abstract

Cardiac resynchronization therapy is an effective treatment method for patients with intraventricular conduction disturbances combined with heart failure and left ventricular systolic dysfunction. The mechanism of resynchronization therapy lies in restoring atrioventricular, intraventricular, and interventricular synchrony, which leads to coordinated ventricular function and improvement in ventricular systolic performance. There are two main methods of resynchronization therapy: biventricular pacing and conduction system pacing. Significant attention is being devoted to conduction system pacing, a relatively new technique that has shown promising results. By many criteria, conduction system pacing, particularly left bundle branch pacing, even surpasses biventricular pacing, which may significantly increase its importance in the near future. In some cases, to achieve better resynchronization effect, methods for resynchronization therapy optimization have been used. These methods involve simultaneous pacing in different loci, as well as the combination of biventricular pacing and conduction system pacing (LOT-CRT, HOT-CRT). This review analyzes the clinical aspects and features of both techniques, along with the advantages and disadvantages of each resynchronization approach.

Article Details

Keywords:

cardiac resynchronization therapy, heart failure, left bundle branch block, conduction system pacing, left bundle branch area pacing, biventricular pacing

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